Novita is dedicated to developing first-in-class drugs to boost anti-cancer immune responses and to prevent and treat cancer metastasis.
Novita is dedicated to developing first-in-class drugs to prevent and treat cancer metastasis and to boost anti-cancer immune responses.
Cancer metastasis is associated with over 90% of cancer related deaths.
A fascin inhibitor would be one of the first drugs to specifically and directly target cancer metastasis.
Novita is developing inhibitors of fascin, a protein involved in cell motility and metastasis, with the aim of targeting the primary cause of over 90% of cancer deaths, for which there is currently no specific drug on the market.
Pre-clinical data demonstrate drug-associated reductions in tumor growth and metastasis, enhanced immune responses and survivals in treated animals, and drug-drug synergism when combined with anti-PD-1 antibodies.
Anti-cancer activity achieved through tandem ability to block tumor metastasis and activate dendritic cells in the tumor microenvironment (TME)
Our data indicate that target-specific anti-fascin agents could have great potential for treating metastatic tumors.
Fascin inhibitors have been shown to block migration and invasion of many tumor types and work synergistically with Immuno-oncology agents to increase overall survival in many cancer models.
Phase 1 clinical trial demonstrates that the drug is well tolerated and signals of anti-tumor activity
Phase 2A clinical trials are being conducted at 15 U.S. cancer centers to further evaluate NP-G2-044 as both monotherapy and in combination with anti-PD-1 agents.
Novita is developing inhibitors of fascin, a protein involved in cell motility and metastasis, with the aim of targeting the primary cause of over 90% of cancer deaths, for which there is currently no specific drug on the market.
Pre-clinical data demonstrate drug-associated reductions in tumor growth and metastasis, enhanced immune responses and survivals in treated animals, and drug-drug synergism when combined with anti-PD-1 antibodies.
Anti-cancer activity achieved through tandem ability to block tumor metastasis and activate dendritic cells in the tumor microenvironment (TME)
Our data indicate that target-specific anti-fascin agents could have great potential for treating metastatic tumors.
Fascin inhibitors have been shown to block migration and invasion of many tumor types and work synergistically with Immuno-oncology agents to increase overall survival in many cancer models.
Phase 1 clinical trial demonstrates that the drug is well tolerated and generates anti-tumor activity
Phase 2A clinical trials are being conducted at 15 U.S. cancer centers to further evaluate NP-G2-044 as both monotherapy and in combination with anti-PD-1 agents.
Novita, a name created to represent “new life”, was founded in 2010 by Drs. Xin-Yun Huang and Jillian Zhang to take their discovery of the novel cancer treatment, fascin inhibitors, from the lab to patients worldwide.
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Posted May 28th, 2024
First Posted: August 26th, 2021 | Updated: February 12, 2024
First Posted June 27th, 2017 | Updated: December 22, 2020
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